1st Day of Organic Chemistry and its Medicinal and Industrial Applications

Liste des Contributions

21. 3D-QSAR STUDY ON ANTIOXIDANT ACTIVITY OF CAFFEIC ACID DERIVATIVES

Dr Abderahmane Belafriekh (Laboratory of LCPMM, Faculty of sciences, University of Blida1, P.O. Box 270 Blida, 09000, Algeria.)

Study of natural substances and their pharmaceutical applications.

Caffeic acid (CA) derivatives are a class of natural compounds found in various sources; these compounds have been shown a huge range of biological activities, such as antioxidant, anti-inflammatory, and anti-diabetic properties. In this study, CA derivatives were collected from literature with antioxidant activity values to generate a 3D-QSAR model. The model was generated successfully with a...

18. Analyse du potentiel antioxydant d'une imine synthétisée à l'aide de calculs électrochimiques

Dr Siham KITOUNI

Synthesis of organic compounds and materials.

1- Synthèse
2- Test de piégeage du radical anion superoxyde par voie électrochimique
3- Conclusion

15. Antifungal Activity of Newly Synthesized Symmetric and Asymmetric Azines: An Experimental and In Silico Study.

khadidja FADLI (Laboratoire de Chimie, Ingénierie Moléculaire et Nanostructures, Université Ferhat Abbas Sétif 1, Sétif, Algeria.)

Synthesis of organic compounds and materials.

The advancements in modern therapeutics are a direct result of numerous research efforts, which have been developed in the fields of synthesis, analysis, and control of pharmaceutical products.
In recent years, it has been demonstrated that organic compounds containing azomethine groups are important compounds in chemistry, biochemistry, and coordination chemistry due to their flexibility,...

24. Antioxidant and Polyphenolic Profiling of Atriplex Species Extracts: Exploring Pharmaceutical Potential of Natural Bioactives

AYA BERKANE (Département de Biochimie et Biologie Cellulaire et Moléculaire, Université Constantine 1)

Study of natural substances and their pharmaceutical applications.

Abstract – The genus Atriplex, part of the Amaranthaceae family, comprises a diverse array of species predominantly inhabiting arid, semi-arid, and saline ecosystems. These plants have garnered significant attention for their bioactive potential, particularly in the context of antioxidant properties. This study investigates the antioxidant efficacy of extracts derived from an Atriplex species,...

12. Comparative Analysis of PVC Nanocomposites Containing Modified and Unmodified Nano-Maghnite: Structural, Thermal, Optical, and Morphological Properties

Dr Badra bouchareb (Research Center in Industrial Technologies CRTI, P.O. Box 64, Cheraga, 16014, Algiers, Algeria.)

Synthesis of organic compounds and materials.

Abstract – Poly(vinyl chloride) (PVC)-Maghnite nanocomposites were prepared by melt blending using a two-roll mixer. This study aims to evaluate the effect of incorporating a natural Algerian clay, Maghnite, extracted from the Roussel deposit in Maghnia (northwest Algeria), on the properties of PVC. This nanofiller was incorporated at low contents (1 to 4 phr) in two forms: raw (RMMT) and...

17. Detection of Chiral Impurity of S-Naproxen Using Vancomycin Chiral Selector

Dr Dehbiya GHERDAOUI (Laboratory of Biomaterials and Transport Phenomena (LBMPT), New Urban Pole, Medea University, Medea 26000, Algeria), Dr Fatma BOUAZZA, Dr samira IHADADENE (Laboratoire d’Analyse Organique Fonctionnelle, Faculté de Chimie, USTHB, B.P. 32, El Alia, Bab Ezzouar 16111, Alger, Algeria)

Abstract
Naproxen (NAP) is a non-steroidal anti-inflammatory drug (NSAID) of the arylacetic acid group, Naproxen is used to relieve the pain, inflammation and stiffness. Enantiomeric purity of naproxen is important, as the R- isomer is hepatotoxic while the S- isomer is safe. Also, the S- isomer of the drug has 28 times than the anti-inflammatory activity of the R- isomer. The use of an...

33. Development and Catalytic Evaluation of Novel Schiff Bases Derived from Dehydroacetic Acid

Dr Tinhinane Louaileche (University Mohamed El Bachir El Ibrahimi . Bordj Bou Arreridj)

Synthesis of organic compounds and materials.

This research examines the synthesis of three Schiff bases, accomplished by the condensation reaction of dehydroacetic acid (DHA) with primary amines.  The resultant compounds were evaluated using several analytical methods, including UV-visible spectroscopy, Fourier-transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR), and melting point determination.
Additionally, the...

22. Développement de nouveaux inhibiteurs de alpha glucosidase : Docking moléculaire, ADMET

Aicha Laoud (Universite constantine3)

Study of natural substances and their pharmaceutical applications.

Dans ce travail nous nous sommes intéressés au développement de nouveaux inhibiteurs potentiels de nt-MGAM afin d’enrichir les classes thérapeutiques des médicaments anti diabète type2. La première étape a constitué en une étude de docking moléculaire, dans le site actif de l’enzyme nt-MGAM, sur un ensemble de dérivées du salacinol afin de déterminer les caractéristiques communes responsables...

14. Experimental Evaluation of Peganum harmala Extracts on Immune System

ALLOUNI Rima (Department of basic studies- natural and life sciences faculty- university of Ferhat Abbas- Setif 1)

Study of natural substances and their pharmaceutical applications.

Peganum harmala L. (Harmel) is a plant traditionally utilized in Algerian medicine for the treatment of various ailments. This study investigates the immunomodulatory effects of two extracts derived from P. harmala seeds: the crude seed extract (CSE) and the total alkaloid extract (TAE). Female NMRI white mice (Mus musculus) were administered CSE (20.72 mg/kg) and TAE (37.75 mg/kg) via...

25. Extraction & Comparative study of activities: Antibacterial, Antifungal and Antioxidant of extracts of essential oils from cumin seeds and fennel seeds.

Dr Fayssal Boudjellal (Laboratoire d’Investigation et de Recherche Spécialisé en Santé, Environnement et Innovation (LIRSSEI))

Study of natural substances and their pharmaceutical applications.

Abstract
Essential oils have important biological activities. Which leads to the study of the biological activity of these essential oils. The aim of this work is to study the antibacterial, antifungal and antioxidant capacities of extracts of cumin and fennel, and to compare the two compounds. The extraction was carried out by hydrodistillation of the clevenger type,...

28. felkaouinourelhouda96@gmail.com

nour el houda Felkaoui (Département de chimie, Faculté des sciences exactes,Laboratoire d'Obtention de Substances Thérapeutiques (L.O.S.T.), Campus Chaabet-Ersas, Université de Constantine 1 , 25000 Constantine)

Study of natural substances and their pharmaceutical applications.

The therapeutic potential of plants from the Lamiaceae family, particularly Mecromeria species, has attracted significant attention in recent years due to their diverse medicinal properties with notable efficacy in addressing a spectrum of health issues, including Alzheimer's disease, cardiovascular disorders, and cancer [1, 2, 3].
Our research aims to evaluate the antioxidant potential of...

23. GREEN SYNTHESIS OF A NOVEL AZOMETHINE DERIVATIVE AS AN ANTIOXIDANT WITH POTENTIAL BIOMEDICAL APPLICATIONS

Ilhem KAABI (Laboratory of Electrochemistry of Molecular Materials and Complexes (LEMMC). Faculty of Technology, Department of Process Engineering. Ferhat Abbas University, DZ-19000, Sétif, Algeria.)

Synthesis of organic compounds and materials.

Abstract
Recognizing the significant body of research on azomethines and their substantial contribution to the scientific literature is essential. These compounds have attracted considerable attention over an extended period and have been widely employed in medicine for the treatment of various disorders. Owing to their remarkable ability to form complexes with metal ions, azomethines are...

19. Iron(II) Complexes with Hydroxy-Substituted Schiff Base Ligands: Synthesis, Characterization, Biological Evaluation, and DFT Analysis

Dr SOUAD DEKAR (Laboratory of Electrochemistry, Molecular Engineering and Redox Catalysis, Faculty of Technology, Ferhat Abbas University, Setif 19000, Algeria.)

Synthesis of organic compounds and materials.

Souad DEKAR1, 2, *, Merzougui Moufida1,3 sabrina bendia1,4 and Kamel OUARI1
1Laboratory of Electrochemistry, Molecular Engineering and Redox Catalysis, Faculty of Technology, Ferhat Abbas University, Setif 19000, Algeria.
2Department of Chemistry, Faculty of Sciences, Ferhat Abbas University, Setif 19000, Algeria.
3 Département Génie de l’Environnement, Faculté des Sciences et de la...

30. L'effet de la liaison hydrogène assistée par résonance sur les propriétés optiques non linéaires du second ordre des photoswitchs à hydrazone de pyridine : une étude de chimie quantique

meriem zaidi (university setif 1- ALGERIA)

Study of natural substances and their pharmaceutical applications.

L’impact des liaisons hydrogène sur les propriétés optiques des hydrazones de pyridine n’avait jusqu’ici pas été considéré comme déterminant. Cependant, cette étude révèle que le contrôle de ces photo-commutateurs dépend étroitement de la force des liaisons hydrogène. Nous examinons ici 18 molécules photo-commutables d’hydrazones de pyridine (isomères E/Z) pour évaluer l’influence des liaisons...

11. L’EXTRACTION ASSISTEE PAR MICRO-ONDES DE PRODUITS NATURELS D’ORIGINE VEGETALE

Razika rouari (pharmacie)

Study of natural substances and their pharmaceutical applications.

L’EXTRACTION ASSISTEE PAR MICRO-ONDES DE PRODUITS NATURELS D’ORIGINE VEGETALE
Rouari Razika¹, Kaarar Mohamed Nadjib¹,2
¹ Laboratoire de chimie analytique, département de pharmacie, faculté de médecine Sétif
2Laboratoire Biopharmacie et Pharmacotechnie, Faculté de médecine, Sétif
Résumé :
L'extraction assistée par micro-ondes (EAM) est une méthode innovante et efficace pour extraire des...

9. Molinspiration and antioxidant studies of novel coumarin derivative

khaoula DOUADI (université Ferhat ABBAS Sétif -1)

Synthesis of organic compounds and materials.

In theory, several methods are available to measure the antioxidant activity of foods and bioactive molecules, these techniques are called following the name of the substance used as a source of free radicals.
In our study, the in vitro antioxidant activity of a new coumarin derivative named MSMet was demonstrated by chemical technique namely: DPPH free radical scavenging, in comparison with...

10. Natural Compounds for Alzheimer’s Disease Treatment: Experimental Evaluation and Molecular Docking Study

Nour El Houda Hammoudi (université de ferhat Abbas Sétif)

Study of natural substances and their pharmaceutical applications.

Alzheimer’s disease (AD) is related to increasing age. It is mainly characterized by progressive neurodegenerative disease, which damages memory and cognitive function. The cholinergic hypothesis is a key theory used to explain the development of Alzheimer's disease (AD). It suggests that AD results from a decline in the neurotransmitter acetylcholine (ACh). Many AD treatments are based on...

29. New hybrid ionic material based on melamine single crystal: synthesis, characterization spectroscopic and thermal behavior

Hakima AIT YOUCEF

Synthesis of organic compounds and materials.

ABSTRACT
Nowadays much attention has been given to hybrid organic–inorganic materials crystals because of their large hyperpolarizabilities and high laser damage resistance compared to inorganic materials. These hybrid materials owing their interesting chemical and physical properties and innovative applications. In this context and devices with innovative properties, we have synthesized a...

27. Quand l’organique rencontre l’industrie pharmaceutique:analyse d’un contraceptif et d’un médicament contre l’ostéoporose

Mlle Djamila Roua AISSAOUI (Université Fehat Abbas)

Study of natural substances and their pharmaceutical applications.

Introduction
La chimie organique constitue la base de la découverte et du développement de nombreux médicaments qui doivent répondre à des critères stricts de sécurité, d’efficacité et d’innocuité, nécessitant un contrôle qualité rigoureux avant toute mise sur le marché.
Cette étude vise à montrer l’application de la chimie dans les domaines médicinal et industriel en vérifiant la...

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Mme Nouara ZIANI

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8. Synthesis and characterization of new ligand polydentate

Bahia BAAZIZ (universite setif 1), Safia DJABBAR (Université des Sciences et de la Technologie Houari Boumediene,)

Synthesis of organic compounds and materials.

Schiff bases are the most widely used organic compounds. They have been shown to exhibit a broad range of biological activities, including antifungal, antibacterial, antimalarial, antiproliferative, anti-inflammatory, antiviral, and antipyretic properties. This work aimed to synthesis the Schiff base. Schiff bases are studied widely due to their synthetic flexibility, selectivity and...

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mansouri mansouri (UFAS)

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31. “Engineering oxide materials for next-generation biological applications”.

Dr Meriem HENNI (Laboratory of synthesis and Catalysis, University of Ibn Khaldoun Tiaret 14000, Algeria), Dr leila DJAHNIT (Hassiba BEN BOUALI university Chlef)

Study of natural substances and their pharmaceutical applications.

Abstract :
Evaluation of the antibacterial activity of our samples α-Fe2O3@Fe3O4 (CS), GO, GO/ α-Fe2O3@Fe3O4 (Hyb.). was carried out using the well diffusion method based on the protocol described by Thana et al [1] with a slight modification. 15ml Muller-Hinton agar was poured into Petri dishes and allowed to solidify. Bacterial cultures were spread evenly over the agar surface and 8mm...